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GitHub
AI Agent·2025
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Biomni: A General-Purpose Biomedical AI Agent

Kexin Huang, Serena Zhang +8

Autonomously executes diverse biomedical research tasks by combining LLM reasoning, retrieval-augmented planning, and code-based execution. Includes a web UI and Gradio demo, a curated Know‑How library, MCP integration, and a biology-tailored reasoning model (Biomni‑R0).

#ai-agent#biology#genomics#drug-discovery#agent-skills+7
GitHub
AI Infra·2025
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Semantica

semantica-agi, Semantica

Provides a deterministic context and knowledge-graph layer under LLMs and vector stores to record auditable decisions, provenance, and explainable rule-based reasoning. Supports polyglot graph storage, W3C PROV-O export, SHACL governance, and self-hosted enterprise connectors.

#mlops#mcp-server#embeddings#reasoning#ai-agent+2
Hugging Face
AI Dataset·2026
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UnsolvedMath

ulamai

Provides a machine-readable collection of 5,426 open and historically significant mathematical problems with LaTeX statements, structured metadata and curated per-problem AI-assisted research notes. Includes difficulty labels, canonical problem sets (Millennium, Hilbert, Erdős) and files optimized for benchmarking math reasoning.

#math#huggingface#benchmark#research#reasoning+1
GitHub
AI Model·2026
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Bonsai Demo

PrismML-Eng, PrismML

Runs the Bonsai family of quantized LLMs locally (including vision-capable 27B): provides scripts and demo UIs to run 1-bit and ternary Bonsai models on macOS (Metal), Linux/Windows (CUDA/Vulkan/ROCm), or CPU, with long context, tool-calling and an optional Open WebUI agent demo.

#llm#vision#multimodal#huggingface#github+5
GitHub
AI Model·2026
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SenseNova-U1

Haiwen Diao, Penghao Wu +8·OpenSenseNova

Unifies multimodal understanding, reasoning, and image generation in a single end-to-end architecture using the NEO-unify paradigm. Models pixels and words jointly without a separate visual encoder, and provides interleaved image–text generation, infographic editing, and GGUF/low‑VRAM inference options.

#multimodal#foundation-model#ai-image#image#transformers+6
Hugging Face
AI Dataset·2026
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Anthropic/BioMysteryBench-full

Anthropic, Hugging Face

A collection of biology-focused 'mystery' tasks for benchmarking model performance on biomedical reasoning, evidence synthesis, and problem solving; curated by Anthropic and hosted on Hugging Face, designed for granular evaluation of scientific decision-making.

#anthropic#huggingface#evaluation#benchmarks#reasoning+1
Hugging Face
AI Dataset·2026
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Nemotron-SFT-Math-v4

NVIDIA Corporation

Provides 545,431 math problems with model-generated solution traces (chain-of-thought and Python tool-integrated reasoning) verified against reference answers for training and evaluating LLM mathematical reasoning. Parquet-format dataset; DeepSeek‑V4‑Pro generated traces and mixed CC BY / CC BY‑SA licensing.

#nvidia#huggingface#math#reasoning#deepseek+4
GitHub
AI Agent·2026
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ADHD — a skill for coding agents

Udit Akhouri·divergent.sh

Spawns parallel, isolated LLM reasoning frames, then scores, clusters and prunes ideas to avoid premature convergence. Packaged as a reusable Claude/Codex agent skill with CLI and TypeScript APIs for ideation, design decisions and fuzzy debugging.

#agent-skills#coding-agents#claude-code#codex#typescript+6
Hugging Face
AI Dataset·2026
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Scaffold-CoT

Specific-Labs

Provides ~3.8M chain-of-thought training examples (~3B tokens) that use a fixed 'Inventory / Interaction / Execution' scaffold to improve concise, reliable reasoning in small LLMs; topic-labeled, deduped, includes real tool-execution traces, CC-BY-4.0.

#reasoning#llm#huggingface#prompt-engineering#benchmarks+1
Hugging Face
AI Dataset·2026
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The Open Distillation Codex

Manusagents

Provides 16M+ instruction–response samples and ~81 GB (7,090 compressed GitHub repos) distilled from 68 open-source sources, organized into 8 categories for SFT, coding agents and reasoning research. Model-generated content; released as a curated MIT-licensed collection.

#code#github#json#llm#ai-coding+5
Hugging Face
AI Model·2026
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Bonsai 27B (1-bit)

Prism ML

Runs a full 27B-class language model using end-to-end binary (1.125-bit) weights, cutting FP16 size to ~3.9 GB. Key features: 262k-token context, custom 1-bit kernels for Apple MLX and CUDA, and an optional DSpark drafter for faster decoding. Best when memory footprint matters; trades some FP16 accuracy for on-device feasibility.

#qwen#llm#huggingface#llama.cpp#reasoning+8
Hugging Face
AI Model·2026
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Ternary Bonsai 27B — GGUF

Prism ML

Provides a 27B-class Qwen3.6-derived language model in GGUF with end-to-end ternary weights (Q2_0_g128), reducing deployed footprint to ~7.2 GB while retaining ~95% of FP16 reasoning ability and enabling on-device 262K-token context inference.

#qwen#llm#foundation-model#huggingface#ai-inference+4
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